|
KMID : 0928520100200020254
|
|
Korean Journal of Lipidology
2010 Volume.20 No. 2 p.254 ~ p.262
|
|
|
Correlation Between Metabolic Syndrome and Pulse Wave Velocity in Korean Women
|
|
Kim Do-yi
Kong Sung-yeol
Song Ha-do
Shin Hyun-ho
|
|
|
Abstract
|
|
|
Objective: Metabolic syndrome (MS) is characterized by a clustering of atherosclerotic cardiovascular risk factors. Pulse wave velocity (PWV) obtained by noninvasive automatic devices is not only an indicator of arterial stiffness but also a marker of vascular damage. Arterial stiffness, assessed by the pulse wave velocity, has also been demonstrated as a predictor for cardiovascular morbidity and mortality. In this study, we investigated the association between the MS and the brachial-ankle pulse wave velocity (baPWV) in Korean women.
Methods: The subjects were 1,583 women (age: 47.4±5.0) who had a standard health check-up at Cheil General Hospital & Women’s Healthcare Center. Arterial stiffness was evaluated by baPWV. Systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), HDL cholesterol, LDL cholesterol, triglyceride (TG), fasting blood sugar (FBS), fasting insulin, homeostatic model assessment insulin resistance (HOMAIR), waist circumference (WC) and body mass index (BMI) were evaluated at the same day. We used a modified National Cholesterol Education Program (NECP) definition of MS for Asian people.
Results: baPWV was significantly higher in those with metabolic syndrome than those without metabolic syndrome (1450.9±251.6 vs. 1230.6±166.2 cm/sec, P<0.01) and increased according to the number of MS components present. Those who had any components of metabolic syndrome showed higher baPWV compared to those without.
Conclusion: The individual risk factors of metabolic syndrome have synergic effect for elevation of arterial stiffness and every factor were associated with the increment of baPWV.
|
|
|
KEYWORD
|
|
|
Metabolic syndrome, Pulse wave velocity, Arterial stiffness, Arteriosclerosis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|